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Le Quere, Herve; Herpin, Amaury; Huvet, Arnaud; Lelong, Christophe; Favrel, Pascal. |
Members of the Transforming Growth factor beta (TGF-beta) superfamily of cell signalling polypeptides are known to play important roles in cell proliferation and differentiation during development and in various physiological processes of most animal clades. Recent findings in the mollusc Crassostrea gigas demonstrate the occurrence of a diversity of TGF-beta signalling components including various ligands, three type I receptors but only a single type II receptor. This report describes the characterization of Cg-ActRII, a new type II receptor displaying homology with vertebrate and Drosophila Activin type II receptors. The use of zebrafish embryo as a reporter organism revealed that, in a way similar to its zebrafish counterpart, overexpression of... |
Tipo: Text |
Palavras-chave: Activin receptor; Nervous tissues; Development; Lophotrochozoa; Mollusc. |
Ano: 2009 |
URL: http://archimer.ifremer.fr/doc/2009/publication-6401.pdf |
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